Table of Contents
Metal-Based Drugs
Volume 2008, Article ID 392090, 7 pages
http://dx.doi.org/10.1155/2008/392090
Research Article

Investigation of Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) Porphyrazine for Application as Photosensitizer in Photodynamic Therapy of Cancer

1Department of Applied Molecular Chemistry, College of Industrial Technology, Nihon University, 1-2-1 Izumi-cho, Narashino-shi, Chiba-ken 275-8575, Japan
2Research Institute of Chemical Science, Technology and Education, 8-37-1 Narashinodai, Funabashi-shi, Chiba-ken 274-0063, Japan
3Nissan Chemical Industries, LTD. Electronic Materials Research Laboratories, 722-1 Tsuboi-cho, Funabashi-shi, Chiba-ken 274-8507, Japan
4U-TEC Corporation, Innovation Technology Development, 21-1 Ohmori-cho, Nara-shi, Nara-ken 630-8131, Japan
5School of Chemical Sciences and Pharmacy, University of East Anglia, Norwich NR4 7TJ, UK

Received 30 June 2007; Revised 22 October 2007; Accepted 5 December 2007

Academic Editor: Jannie C. Swarts

Copyright © 2008 Keiichi Sakamoto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. B. McKeown, Phthalocyanine Materials—Synthesis Structure and Function, Cambridge University Press, Cambridge, UK, 1998.
  2. C. C. Leznff and A. B. P. Lever, Phthalocyanines—Properties and Applications, vol. 1–4, VCH, New York, NY, USA, 1989, 1993, 1996.
  3. R. Hirohashi, K. Sakamoto, and E. Ohno-Okumura, Phthalocyanines as Functional Dyes, ICP, Tokyo, Japan, 2004.
  4. I. Okura, Photosensitization of Porphyrins and Phthalocyanines, Kodansya, Tokyo, Japan, 2000.
  5. G. Jory, “Photosensitised processes in vivo: Proposed phototherapeutic applications,” Photochemistry and Photobiology, vol. 52, pp. 439–443, 1990. View at Google Scholar
  6. J. Moan, “Properties for optimal PDT sensitizers,” Journal of Photochemistry and Photobiology. B, Biology, vol. 5, no. 3-4, pp. 521–524, 1990. View at Publisher · View at Google Scholar
  7. M. J. Cook, I. Chambrier, S. J. Cracknell, D. A. Mayes, and D. A. Russell, “Octa-alkyl zinc phthalocyanines: potential photosensitizers for use in the photodynamic therapy of cancer,” Photochemistry and Photobiology, vol. 62, no. 3, pp. 542–545, 1995. View at Google Scholar
  8. K. Tabata, K. Fukushima, K. Oda, and I. Okura, “Selective aggregation of zinc phthalocyanines in the skin,” Journal of Porphyrins and Phthalocyanines, vol. 4, no. 3, pp. 278–284, 2000. View at Publisher · View at Google Scholar
  9. K. Sakamoto, T. Kato, and M. J. Cook, “Position isomer separation of non-peripheral substituted zinc dibenzo-di(3,4-pyrido)porphyrazines,” Journal of Porphyrins and Phthalocyanines, vol. 5, no. 10, pp. 742–750, 2001. View at Publisher · View at Google Scholar
  10. K. Sakamoto, T. Kato, T. Kawaguchi et al., “Photosensitizer efficacy of non-peripheral substituted alkylbenzopyridoporphyrazines for photodynamic therapy of cancer,” Journal of Photochemistry and Photobiology A: Chemistry, vol. 153, no. 1–3, pp. 245–253, 2002. View at Publisher · View at Google Scholar
  11. K. Sakamoto, E. Ohno-Okumura, T. Kato, T. Kawaguchi, and M. J. Cook, “Laser-flash photolysis of dialkylbenzodipyridoporphyrazines,” Journal of Porphyrins and Phthalocyanines, vol. 7, no. 2, pp. 83–88, 2003. View at Google Scholar
  12. K. Sakamoto, T. Kato, E. Ohno-Okumura, M. Watanabe, and M. J. Cook, “Synthesis of novel cationic amphiphilic phthalocyanine derivatives for next generation photosensitizer using photodynamic therapy of cancer,” Dyes and Pigments, vol. 64, no. 1, pp. 63–71, 2005. View at Publisher · View at Google Scholar
  13. I. Seotsanya-mokhosi, N. Kuznetsova, and J. T. Nyokong, “Photochemical studies of tetra-2,3-pyridinoporphyrazines,” Journal of Photochemistry and Photobiology A: Chemistry, vol. 140, no. 3, pp. 215–222, 2001. View at Publisher · View at Google Scholar
  14. M. Yokote, F. Shibamiya, and S. Shoji, “On the copper phthalocyanine-N-isolog (copper tetra-3,4-pyridoporphyrazine) obtained from Cinchomeronic acid,” Kogyo Kagaku Zasshi, vol. 67, pp. 166–176, 1964. View at Google Scholar
  15. K. Sakamoto and F. Shibamiya, “Reaction of copper diberzodipyridoporphyrazine with diethylsulfate,” Journal of the Japan Society of Colour Material, vol. 59, pp. 517–524, 1986. View at Google Scholar
  16. K. Kadish, G. Moninot, Y. Hu et al., “Double-decker actinide porphyrins and phthalocyanines. Synthesis and spectroscopic characterization of neutral, oxidized, and reduced homo- and heteroleptic complexes,” Journal of American Chemical Society, vol. 115, pp. 8153–8166, 1993. View at Publisher · View at Google Scholar