Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy
Figure 3
Electron microscopic analysis of L. donovani AG83 cells treated with 0.2% DMSO alone and 20 μM CLP for different time periods. Spur blocks were prepared as described in Section 2. (a) Control cells treated with 0.2% DMSO alone, (b) cells treated with 20 μM CLP for 2 h, and (c) cells treated with 20 μM CLP for 6 h. Scale bars are indicated in the figure. N: nucleus, CV: cytoplasmic vacuoles, FN: fragmented nucleus, and closed arrow represents membrane blebbing.
