Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy
Figure 6
Determination of intracellular GSH level and level of lipid peroxidation in response to CLP treatment. (a) Level of intracellular GSH in treated and untreated L. donovani promastigotes. The intracellular GSH level was measured after treatment with 0.2% DMSO (closed circles), 20 μM CLP (closed squares) and with NAC (20 mM) before treatment with CLP (closed triangles). (b) The level of fluorescent products of lipid peroxidation was measured after treatment of leishmanial cells with 0.2% DMSO (closed circles), 20 μM CLP (closed squares) and with NAC (20 mM) before treatment with CLP (closed triangles). Data are represented as Mean ± SEM ().
