Cryptolepine-Induced Cell Death of Leishmania donovani Promastigotes Is Augmented by Inhibition of Autophagy

Table 2

Fold of expression and corresponding fold change of ATG 8 and Sir2 genes relative to internal GAPDH control in treated samples compared with the untreated control.

Condition	ATG 8		Sir2
	Mean fold expression	Fold change	Mean fold expression	Fold change
Control + 3-MA (6 hrs)	0.867571	~−1.2	1.132042	~1.1
Control + CLP (2 hrs)	2.936239	~3	2.697552	~2.7
Control + 3-MA + CLP (2 hrs)	1.126242	~1.1	0.873598	~−1.1
Control + CLP (6 hrs)	1.310307	~1.3	1.460229	~1.5
Control + 3-MA + CLP (6 hrs)	0.774112	~−1.3	0.659147	~−1.5