Table 1: Changing therapeutic response to pentavalent antimonials (Adapted from T. K. Jha, 2006 [219]).

StudyDose (mg/kg/day)Duration (days)No. of coursesNo. of casesUnresponsiveness (%)

Jha, (1980) [220]1010120017

Thakur et al., (1984) [221]20201648
>201620

Jha, (1986) [222]Child-20Fresh-301Fresh-731.1
Adult-10Relapse-601Relapse-17
Slow1
response-42

Thakur et al., (1988) [223]1040137126
15114
2013

Jha, (1992) [224]2030125227.1

Jha, (1995) [225]203013225

Jha, (1998) [226]203013037

Thakur et al., (1998) [227]203018054

Sundar et al., (2001) [102]2030118460