Restriction of Retroviral Replication by Tetherin/BST-2

Figure 1

Schematic representation of tetherin domain structure. Tetherin is depicted as a parallel dimer with both transmembrane (TM) and glycophosphatidylinositol (GPI) membrane anchors in the same membrane. Disulfide linkages are depicted in green, and N-linked glycosylation sites pictured. CC: coiled coil; Y: tyrosine residues critical for endocytic motif.