The RASSF1 Gene and the Opposing Effects of the RASSF1A and RASSF1C Isoforms on Cell Proliferation and Apoptosis
Figure 9
Assessment of RASSF1A and RASSF1C mRNA expression was carried out in 15 lung adenocarcinomas and matched normal tissues using RT-PCR. (a) RASSF1A was downregulated in 53% (8/15) and upregulated in 20% (3/15) and (b) RASSF1C was downregulated in 53% (8/15) and upregulated in 47% (7/15) of the lung adenocarcinomas tested.