Investigation of the Association between Genetic Polymorphism of Microsomal Epoxide Hydrolase and Primary Brain Tumor Incidence

Table 5

HWE for polymorphisms in mEH exon 3 and 4.

	Control		Patients
Genotypes	Observed	Expected	Observed	Expected
Exon 3
Homozygote reference	83	81.4	58	57.4
Heterozygotes	55	58.2	37	38.3
Homozygotes variant	12	10.4	7	6.4
Variance allele frequency	0.26		0.25
𝜒^2 test 𝑃 value; (if < 0.05 not consistent with HWE)	0.79		0.94
Exon 4
Homozygote reference	104	106.7	85	85.1
Heterozygotes	45	39.6	19	18.9
Homozygotes variant	1	3.7	1	1.1
Variance allele frequency	0.16		0.10
𝜒^2 test 𝑃 value; (if < 0.05 not consistent with HWE)	0.25		0.99