FOXO3a Gene Polymorphism Associated with Asthma in Indian Population

Table 5

Distribution of the rs13217795, C>T polymorphism according to gender in the study groups.

Gender		Males		Females
		Asthmatic patients ()	Healthy controls ()	Asthmatic patients ()	Healthy controls ()
Genotype	CC	9 (13.04%)	40 (51.28%)	2 (4.44%)	32 (50%)
	CT	33 (47.82%)	29 (37.17%)	11 (24.44%)	23 (35.93%)
	TT	27 (39.13%)	9 (11.54%)	32 (71.11%)	9 (14.06%)
Allele	C	51 (36.95%)	109 (69.87%)	15 (16.66%)	87 (67.96%)
	T	87 (63.04%)	47 (30.12%)	75 (83.33%)	41 (32.03%)

Odds ratio from genotypic frequency:
Males: odds ratio keeping CC as baseline:
CT—5.057; 95% confidence interval = 2.10 to 12.174.
TT—13.33; 95% confidence interval = 4.689 to 37.911.
Females: odds ratio keeping CC as baseline:
CT—7.652; 95% confidence interval = 1.5463 to 37.867.
TT—56.88; 95% confidence interval = 11.386 to 284.219.
Odds ratio from allelic frequency:
Males: odds ratio = 3.9562; 95% confidence interval = 2.432 to 6.433.
Females: odds ratio = 10.6098; 95% confidence interval = 5.4442 to 20.67.