Cloning, Sequencing, and the Expression of the Elusive Sarcomeric TPM4α Isoform in Humans

Figure 1

Alternative splicing pattern of the TPM4 gene in humans. Exon composition of the TPM4 gene is derived from the published documents (top) and the recently submitted data in GenBank. Although the splice variants TPM4β (NM_001145160) and TPM4γ (NM-003290.2) are known for some time, the cartoons of the splice variants of TPM4α and TPM4δ are generated with the information of the recently submitted sequences of the corresponding predicted isoforms in GenBank as well as the results from the present study. Exon locations of primers P1(+), P2(−), and P3(+) are shown.