Fatal Mimicry: Oral Melanoma versus Mantle Cell Lymphoma

Margolin, L.; Monselise, A.

doi:https://doi.org/10.3814/2010/581923

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Case Report | Open Access

Volume 2010 | Article ID 581923 | https://doi.org/10.3814/2010/581923

Fatal Mimicry: Oral Melanoma versus Mantle Cell Lymphoma

L. Margolin¹and A. Monselise²

Received15 Oct 2009

Revised18 Jan 2010

Accepted09 Feb 2010

Published30 Mar 2010

Abstract

We present a 71-year-old male with oral melanoma and mantle cell hyperplasia who was erroneously diagnosed and treated as mantle cell lymphoma. The differential diagnosis of MCL versus mantle cell hyperplasia is a challenging task. Thorough immunohistochemical and cytogenetic analyses are warranted before treatment administration. The more common presentation of amelanotic malignant melanoma requires a high index of suspicion for masses identified in the mouth and requires biopsy for definitive diagnosis. A meticulous physical examination is advocated.

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Copyright

Copyright © 2010 L. Margolin and A. Monselise. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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