The Number of Frames on ECG-Gated ¹⁸F-FDG Small Animal PET Has a Significant Impact on LV Systolic and Diastolic Functional Parameters

Figure 4

Comparison of the LV volumes and functional parameters of all animals (, ) with different numbers of frames per cardiac cycle using Holm-Sidak’s multiple comparison test with 16 frame data as reference. The LV volumes (EDV, ESV, and SV) of the 4, 8, and 12 frame data differ significantly from the reference, whereas for EF and diastolic parameters (TPF, 1/3 FR, and PFR), no significant difference between the reconstruction with 12 gates per cycle and the reference was recorded. EDV: end-diastolic volume; ESV: end-systolic volume; SV: stroke volume; EF: ejection fraction; TPF: time to peak filling; 1/3FR: first third filling rate; PFR: peak filling rate. Statistically significant vs. 16 frames per cardiac cycle ().