Early Changes in [¹⁸F]FDG Uptake as a Readout for PI3K/Akt/mTOR Targeted Drugs in HER-2-Positive Cancer Xenografts

Figure 5

Representative images of JIMT1 xenografts. Representative [¹⁸F]FDG PET/CT SUV-corrected images of mice exposed to monotherapy and combination therapy at baseline and after day 7. White arrows indicate tumors with the SUV_max of that tumor. Mice treated with monotherapy are imaged in prone position and mice treated with combination therapy in supine position.