Automated Synthesis and Initial Evaluation of (4-Amino-5,8-difluoro-1H-spiro[piperidine-4,2-quinazolin]-1-yl)(4-[¹⁸F]fluorophenyl)methanone for PET/MR Imaging of Inducible Nitric Oxide Synthase

Table 1

Comparison of PET standardized uptake value (SUV) and standardized uptake value ratio (SUR) of [¹⁸F]FBAT in control vs. LPS mice at 3 or 24 h post i.v. injection of LPS (SUR_LPS to SUV_con).

SUV	Control	LPS 3 h	LPS 24 h	LPS 3 h+AMG
Whole brain
SUR	1.000			N/A
Cortex
SUR	1.000			N/A
Cerebellum
SUR	1.000			N/A
Brainstem
SUR	1.000			N/A

Data are ; per group; , , and compared to controls; ^#, ^##, and ^### compared to LPS 3 h.