Research Article
Neuroinflammation in Low-Level PM2.5-Exposed Rats Illustrated by PET via an Improved Automated Produced [18F]FEPPA: A Feasibility Study
Table 1
The QC tests of the [18F]FEPPA (2).
| | Items tested | Acceptance criteria | | Visual inspection | Clear, colorless solution | Pass | Pass | Pass |
| | pH value | 5-8 | 7 | 7 | 7 | | Residual K2.2.2 (μg/mL) | <50 | <50 | <50 | <50 | | Radionuclidic purity (%) | >99.5 | 99.93 | 99.96 | 99.62 | | Half-life (min) | | 108 | 115 | 115 | | Radiochemical identity (min) | ∣Rt-Rt (reference)∣≤0.5 | 0.02 | 0.00 | 0.07 | | Radiochemical purity (%) | >90 | 99.9 | 99.8 | 99.8 | | Residual solvent analysis |
| 4.6849%
0.1454%
0.0100% | 0.1673%
0.0324%
0.0014% | 2.2298%
0.0010%
0.0008% | | Residual [18F]Fluoride (%) | <5 | 0.01 | 0.02 | 0.59 | | Bacterial endotoxins (EU/V) | <175 | <17.5 | <17.5 | <17.5 | | Filter integrity test (psi) | >45 | 48.5 | 46.6 | 46.0 | | Sterility test | Sterile | Sterile | Sterile | Sterile |
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