Evaluation of [¹⁸F]tetrafluoroborate as a Potential PET Imaging Agent in a Sodium Iodide Symporter-Transfected Cell Line A549 and Endogenous NIS-Expressing Cell Lines MKN45 and K1

Figure 7

Static scans of [¹⁸F]TFB in mice bearing MKN45, K1, A549, and NIS-A549 cells at 1 h PET images of [¹⁸F]TFB distribution at at 1 h i.v. in mice bearing (a) MKN45, (b) A549 and NIS-A549 cells, and (c) K1 showing uptake in the thyroid (Th), stomach (St), bladder (BL), salivary gland, and tumor tissue. White cross targets designate the location of NIS⁺ tumors. White arrows designate location of NIS^- tumor without detectable uptake of [¹⁸F]TFB.