Review Article
Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors
Table 6
Summary of PSMA-targeted imaging in meningiomas.
| | Authors | Year | | PSMA tracer | Main results |
| | Bilgin et al. | 2016 | 1 | 68Ga-PSMA | (i) High 68Ga-PSMA uptake in brain lesion (SUVmax 3.1), diagnosed as meningioma on MRI | | Jain et al. | 2017 | 1 | 68Ga-PSMA | (i) Avid 68Ga-PSMA uptake in meningioma (SUVmax 1.9) but no FDG avidity | | Sasikumar et al. | 2017 | 1 | 68Ga-PSMA | (i) Stronger 68Ga-PSMA uptake (SUVmax 14.6, TBR 29.2) than FDG (SUVmax 6.44, TBR 0.74)
(ii) Meningioma diagnosis confirmed by pathology | | Gupta et al. | 2020 | 1 | 68Ga-PSMA | (i) Avid 68Ga-PSMA uptake, diagnosis confirmed by MRI | | Courtney et al. | 2021 | 1 | 68Ga-PSMA | (i) 68Ga-PSMA uptake demonstrated in a meningioma | | Junqueira et al. | 2021 | 1 | 68Ga-PSMA | (i) Strong 68Ga-PSMA uptake demonstrated in an intraventricular meningioma (SUVmax 12.1) | | Calabria et al. | 2017 | 1 | 64Cu-PSMA | (i) 64Cu-PSMA uptake in MRI-confirmed meningioma was SUVmax 3.8 at 1 h postinjection, 3.9 at 4 h postinjection | | Haemels et al. | 2020 | 1 | 18F-PSMA | (i) Moderately avid 18F-PSMA uptake in pathology-confirmed meningioma |
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