Research Article

Application of Dynamic 18F-FDG PET/CT for Distinguishing Intrapulmonary Metastases from Synchronous Multiple Primary Lung Cancer

Figure 2

Dynamic acquisition mode and Patlak model. (a) Dynamic data were collected for 60 min comprising 48 frames: , , , , , and . (b) The Patlak plot has been developed for systems with irreversible trapping (). Most often it is applied for the analysis of FDG. and describe the 18F-FDG exchange between arterial plasma and tissue; and describe the exchange between 18F-FDG and 18F-FDG-6PO4 in tissue. As a result of unidirectional uptake of 18F-FDG, . represents the 18F-FDG net uptake rate constant, i.e., .
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