Application of Dynamic ¹⁸F-FDG PET/CT for Distinguishing Intrapulmonary Metastases from Synchronous Multiple Primary Lung Cancer

Table 3

Individual results in the sMPLC group.

Patient no.	Location of tumor 1	Pathological subtype	8th TNM stage	(cm)		(min^-1)	Location of tumor 2	Pathological subtype	8th TNM stage	(cm)		(min^-1)
1	LUL	Papillary	pT1cN0M0, IA3	1.80	3.15	0.0201	RUL	Acinar	pT1bN2M0, IIIA	1.60	2.72	0.0218	0.05	0.0025
2	LUL	Invasive mucinous AC	pT1aN0M0, IA1	1.30	1.61	0.0192	LLL	Acinar	pT1aN0M0, IA1	1.50	0.27	0.0012	1.06	0.0140
3	LUL	Acinar	pT1bN0M0, IA2	1.20	0.32	0.0006	LLL	AC	pT1aN0M0, IA1	0.40	0.59	0.0015	1.20	0.0032
4	RUL	Acinar	pT1cN0M0, IA3	2.20	2.87	0.0089	RML	Lepidic	pT1aN0M0, IA1	0.80	0.41	0.0009	0.80	0.0030
5	RUL	Acinar	pT1cN0M0, IA3	1.80	1.67	0.0068	RLL	Lepidic	pT1bN0M0, IA2	1.00	0.91	0.0019	0.02	0.0019
6	RUL	Minimally invasive AC	pT1bN0M0, IA2	1.50	0.82	0.0006	LUL	Acinar	pT1cN0M0, IA3	2.80	1.59	0.0034	0.02	0.0008
7	LUL	Acinar	pT2bN0M0, IIA	5.50	1.47	0.0024	RUL	Papillary	pT2aN2M0, IIIA	5.20	3.85	0.0169	0.47	0.0028
8	RUL	Lepidic	pT1bN0M0, IA2	0.90	0.46	0.0007	RUL	Acinar	pT1aN0M0, IA1	0.90	0.89	0.0014	0.48	0.0007
9	RUL	Papillary	pT1bN0M0, IA2	1.20	0.62	0.0049	RLL	Acinar	pT1aN0M0, IA1	0.30	0.80	0.0006	2.16	0.0022
10	RLL	Acinar	pT1bN0M0, IA2	0.70	0.66	0.0011	RUL	Minimally invasive AC	pT1aN0M0, IA1	0.30	0.69	0.0004	1.37	0.0004
11	RUL	Acinar	pT2aN2M0, III A	3.00	8.76	0.0312	LLL	—	cT1aNxM0	1.00	0.84	0.0012	2.08	0.0093
12	RUL	Acinar	pT1bN0M0, IA2	1.20	0.62	0.0006	RLL	Papillary	pT1aN0M0, IA1	0.60	0.88	0.0038	0.96	0.0058
13	RUL	Minimally invasive AC	pT1aN0M0, IA1	0.60	0.95	0.0004	RLL	Acinar	pT1bN0M0, IA2	1.30	0.56	0.0004	1.16	0.0004
14	LLL	Acinar	pT1cN0M0, IA3	2.00	4.10	0.0206	RML	—	cT1aN0M0, IA1	0.60	0.37	0.0006	1.43	0.0094
15	RLL	Acinar	pT1cN0M0, IA3	3.10	1.65	0.0071	RUL	—	cT1aN0M0, IA1	0.50	0.79	0.0019	1.05	0.0014
16^a	RML	Acinar	pT1aN0M0, IA1	2.00	0.48	0.0014	RLL	Acinar	pT2aN0M0, IB	2.90	0.95	0.0055	0.09	0.0012
17	RUL	—	cT1cN0M0, IA3	2.60	3.25	0.0120	RLL	AC	cT2bN0M0, IIA	4.60	4.45	0.0224	0.28	0.0003
18	RUL	Acinar	pT1bN0M0, IA2	2.00	0.93	0.0028	RLL	Minimally invasive AC	pT1aN0M0, IA1	0.50	0.60	0.0015	0.73	0.0017
19	LUL	—	cT1aN0M0, IA1	0.50	0.42	0.0005	RLL	Acinar	pT1aN0M0, IA1	0.90	0.55	0.0003	0.22	0.0007
Median (min–max)													0.96 (0.02-2.16)	0.0019 (0.0003-0.0140)

^aSpecifically, tumor 1 and tumor 2 in patient no. 16 have the same pathological subtype, but the different gene mutation. sMPLC: synchronous multiple primary lung cancer; : largest diameter of tumor 1; : largest diameter of tumor 2; : influx rate constant; SUV_max: maximum standardized uptake value; : SUV_max of tumor 1; : SUV_max of tumor 2; : of tumor 1; : of tumor 2; : absolute difference between and ; : absolute difference between and ; RUL: right upper lobe; RML: right middle lobe; RLL: right lower lobe; LUL: left upper lobe; LLL: left lower lobe; AC: adenocarcinoma. Blank represents not available or there is no corresponding detection.