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Malaria Research and Treatment
Volume 2011, Article ID 414510, 4 pages
Research Article

Pattern of the Antimalarials Prescription during Pregnancy in Bangui, Central African Republic

1Institut Pasteur of Bangui, Epidemiology Service, P.O. Box 923, Pasteur Avenue, Bangui, Central African Republic
2Centre de Formation et de Recherche en Médecine et Santé Tropicales, Faculté de Médecine Nord, Boulevard Dramard, 13015 Marseille, France
3Association Altersanté, Centre Médical de Bligny, 91640 Briis-sous-Forges, France
4Ministère de la Santé, de la Population et de Lutte Contre le VIH-SIDA, National Malaria Control Service, P.O. Box 143, Central African Republic
5Ministère de la Santé, de la Population et de Lutte Contre le VIH-SIDA, Health Centre of Castors, Bangui, P.O. Box 143, Central African Republic
6Université de Nancy, CHU de Nancy, Hôpital de Brabois-adultes, 54511 Vandoeuvre-lès-Nancy Cedex, France

Received 6 February 2011; Accepted 8 June 2011

Academic Editor: Valery Combes

Copyright © 2011 Alexandre Manirakiza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. The aim of this study was to identify the antimalarials prescribed during the pregnancy and to document their timing. Method. From June to September 2009, a survey was conducted on 565 women who gave birth in the Castors maternity in Bangui. The antenatal clinics cards were checked in order to record the types of antimalarials prescribed during pregnancy according to gestational age. Results. A proportion of 28.8% ANC cards contained at least one antimalarial prescription. The commonest categories of antimalarials prescribed were: quinine (56.7%), artemisinin-based combinations (26.8%) and artemisinin monotherapy (14.4%). Among the prescriptions that occurred in the first trimester of pregnancy, artemisinin-based combinations and artemisinin monotherapies represented the proportions of (10.9%) and (13.3%). respectively. Conclusion. This study showed a relatively high rate (>80%) of the recommended antimalarials prescription regarding categories of indicated antimalarials from national guidelines. But, there is a concern about the prescription of the artemisinin derivatives in the first trimester of pregnancy, and the prescription of artemisinin monotherapy. Thus, the reinforcement of awareness activities of health care providers on the national malaria treatment during pregnancy is suggested.