Characterization of the Duffy-Binding-Like Domain of Plasmodium falciparum Blood-Stage Antigen 332

Table 1

Prevalence of seropositivity for antibodies against Pf332-DBL and PfEMP1-DBL1α.

		Pf332-DBL	PfEMP1-DBL1α
Countries (ethnic group)	n	No. (%) of responders^1	No. (%) of responders^1	P value^2
Uganda, Kampala	120	72 (60.0)	82 (68.3)	ns
Uganda, Apac, mild malaria	39	29 (74.4)	28 (71.8)	ns
Uganda, Apac, severe malaria	31	26 (83.9)	27 (87.1)	ns
Burkina Faso (Fulani)	60	57 (95.0)	31 (51.7)	<0.0001
Burkina Faso (Mossi)	48	47 (97.9)	35 (72.9)	0.0008
Mali (Fulani)	28	26 (92.9)	20 (71.4)	ns
Mali (Dogon)	32	30 (93.8)	16 (50.0)	0.0002

¹Cutoff threshold for seropositivity was determined as the mean OD₄₀₅ value plus 3 SD of a pool of nonimmune Swedish donors.
²P values by Chi-square test at a <0.05 significance level (ns = not significant).