In Vivo Hemozoin Kinetics after Clearance of Plasmodium berghei Infection in Mice

Figure 4

Hemozoin deposition in the spleen of malaria infected-cured mice. Representative images of hemozoin (Hz) deposition in the spleen of P. berghei NK65 infected-cured mice at different times after the end of Chloroquine treatment. Sections of spleen of infected-cured mice showed a majority of the Hz deposition in the red pulp (as indicated by the black arrows). The Hz aggregates seemed to become larger over time (bottom row).