Antimalarial Effects of Iranian Flora Artemisia sieberi on Plasmodium berghei In Vivo in Mice and Phytochemistry Analysis of Its Herbal Extracts

Figure 4

Pathophysiological alterations induced by A. sieberi ether and chloroform extracts in malarial animals. Pathophysiological alterations including body weight, survival rate, and hepato/splenomegaly were evaluated as indices of toxicity by ether and chloroform extracts of A. sieberi in control and malarial groups (test, A. sieberi ether and chloroform extracts; control, drug vehicle, 𝑛=10 mice/day/group, Student’s t-test, *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001).

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