Malaria Research and Treatment / 2013 / Article / Tab 4

Clinical Study

Amodiaquine-Artesunate versus Artemether-Lumefantrine against Uncomplicated Malaria in Children Less Than 14 Years in Ngaoundere, North Cameroon: Efficacy, Safety, and Baseline Drug Resistant Mutations in pfcrt, pfmdr1, and pfdhfr Genes

Table 4

Mean variation in haematological and biochemical indices 14 days after treatment.

ParameterAS/AQAL
Mean ± SDPaired -test Mean ± SD value+

Haematocrit (%)
 D068 69
 D1468 0.8769 0.66
WBCs (×103/ L)
 D068 69
 D1468 0.04*69 0.026*
Platelets (×103/ L)
 D068 69
 D1468 0.001*69 0.002*
ALAT (U/L)
 D068 69
 D1468 0.2569 0.17
Creatinine (mg/L)
 D068 69
 D1468 0.1769 0.019*
Bilirubin (mg/L)
 D068 69
 D1468 0.9569 0.43

Indices were measured at pre-treatment and on day 14. Values are reported as mean readings ± standard deviation of patients treated with AS/AQ or AL.
: number, SD: standard deviation, ALAT: alanine transaminase, and *significant at threshold of . +Paired students’ -test.

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