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Malaria Research and Treatment
Volume 2014, Article ID 390513, 7 pages
Research Article

Mother-to-Children Plasmodium falciparum Asymptomatic Malaria Transmission at Saint Camille Medical Centre in Ouagadougou, Burkina Faso

1Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso
2Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso
3University St. Thomas Aquinas of Ouagadougou, 06 P.O. Box 10212, Ouagadougou 06, Burkina Faso
4Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso
5Laboratory of Molecular and Cellular Biology, University of Science and Technique of Masuku (USTM), P.O. Box 943, Franceville, Gabon
6Department of Biology, UNESCO Chair in Biotechnology, Laboratory of Immunology & Pathology, University of Rome Tor Vergata, Scientific Research Avenue snc, 00143 Rome, Italy

Received 8 September 2014; Accepted 1 November 2014; Published 23 November 2014

Academic Editor: Polrat Wilairatana

Copyright © 2014 Zoenabo Douamba et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Malaria’s prevalence during pregnancy varies widely in parts of sub-Saharan Africa, including Burkina Faso. The objective of this study was to evaluate the incidence of mother-to-child malaria transmission during childbirth at St. Camille Medical Centre in the city of Ouagadougou. Methods. Two hundred and thirty-eight (238) women and their newborns were included in the study. Women consenting to participate in this study responded to a questionnaire that identified their demographic characteristics. Asymptomatic malaria infection was assessed by rapid detection test Acon (Acon Malaria Pf, San Diego, USA) and by microscopic examination of Giemsa-stained thick and thin smears from peripheral, placental, and umbilical cord blood. Birth weights were recorded and the biological analyses of mothers and newborns’ blood were also performed. Results. The utilization of long-lasting insecticidal nets (LLINs) and intermittent preventive treatment with sulfadoxine-pyrimethamine (SP) were 86.6% and 84.4%, respectively. The parasitic infection rates of 9.5%, 8.9%, and 2.8% were recorded, respectively, for the peripheral, placental, and umbilical cord blood. Placental infection was strongly associated with the presence of parasites in the maternal peripheral blood and a parasite density of >1000 parasites/µL. Conclusion. The prevalence of congenital malaria was reduced but was associated with a high rate of mother-to-child malaria transmission.