Review Article

Exploiting Unique Structural and Functional Properties of Malarial Glycolytic Enzymes for Antimalarial Drug Development

Figure 1

Unique structural differences between P. falciparum (PfTPI) (a) and human TPI (HsTPI) (b). Unique residues in PfTPI and their counterparts in HsTPI are labeled. PDB IDs of PfTPI and HsTPI are 1YDV and 1WYI, respectively. Structures were visualized by molecular visualization software PyMOL (DeLano Scientific).
(a)
(b)