Effect of Iron/Folic Acid Supplementation on the Outcome of Malaria Episodes Treated with Sulfadoxine-Pyrimethamine

Table 1

Hospitalizations at 15 days, 30 days, and 140 days following SP treatment.

Groups	𝑁	Day 15		Day 30		Day 140
SP and		𝑛	RR (95% CI)	𝑛	RR (95% CI)	𝑛	RR (95% CI)
Placebo	552	17	—	23	—	63	—
Folic acid	1096	25	0.73 (0.38–1.45)	39	0.85 (0.49–1.49)	119	0.95 (0.69–1.30)
Fe/FA	550	14	0.82 (0.38–1.77)	19	0.82 (0.42–1.58)	62	0.99 (0.68–1.42)
Fe/FA/Zn	546	11	0.65 (0.27–1.46)	20	0.87 (0.46–1.67)	57	0.90 (0.62–1.32)

SP: sulfadoxine and pyrimethamine; Fe: iron; FA: folic acid; Zn: zinc.
Folic acid = Fe/FA and Fe/FA/Zn groups.