Research Article

Evaluation of the Quality of Artemisinin-Based Antimalarial Medicines Distributed in Ghana and Togo

Table 5

Quality of the categories of antimalarial medicines by HPLC assay.

Categories of antimalarialsGhanaTogoOverall failure rate
TotalNumber testedFail% failureTotalNumber testedFail% failure

ACTs (90)
 Artesunate141212100%111111100%
 Artemether31302273.3%28282485.7%72/86 = 83.7%
 Dihydroartemisinin 44250%211100%
Artemisinin-based monotherapy (42)
 Artesunate (oral)333100%111111100%
 Artemether (parenteral)1100%2117529.4%22/38 = 57.9%
 Dihydroartemisinin (oral) 55360%1100%