Role of Different Pfcrt and Pfmdr-1 Mutations in Conferring Resistance to Antimalaria Drugs in Plasmodium falciparum

Table 2

List of mutations in pfmrp of Plasmodium falciparum along with properties of both substituent and substituted amino acids.

Site of mutation	Substituted amino acids	Side chain polarity	Side chain charge	Hydrophobicity index	Substituent amino acid	Side chain polarity	Side chain charge	Hydrophobicity index
191	Tyrosine	Polar	Neutral		Histidine	Basic; polar	Partially positive
437	Alanine	Non polar	Neutral		Serine	Polar	Neutral