Efficacy and Safety of Artesunate-Amodiaquine versus Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium falciparum Malaria in Sentinel Sites across Côte d’Ivoire

Table 4

Changing patterns for biological parameters in the two groups.

	ASAQ				AL
	D1	D4	D1–D4		D1	D4	D1–D4
Haemoglobin (g/dL) (SD)	10 (1.75)	9.14 (1.78)	0.86 (−0.03)	0.000045	10 (1.89)	8.98 (1.85)	1.02 (0.04)	0.0001
AST (IU/L) (SD)	34.66 (19.4)	29.79 (18.58)	4.87 (0.82)	0.031	36.50 (20.43)	35.44 (67.57)	1.06 (−47.14)	0.533
ALT (IU/L) (SD)	33.01 (14.26)	22.46 (14.57)	10.55 (−0.31)	0.747	23.07 (13.96)	21.61 (12.12)	1.46 (1.84)	0.344
Bilirubin (mg/L) (SD)	9.23 (7.65)	5.89 (5.07)	3.34 (2.58)	0.0002	8.66 (8.71)	5.49 (5.22)	3.17 (3.49)	0.0002
Creatinine (mg/L) (SD)	8.44 (2.96)	8.51 (2.92)	−0.07 (0.04)	0.840	8.0 (2.18)	7.49 (2.26)	0.51 (−0.08)	0.056

Paired -test.