Research Article
Major Polymorphisms of Genes Involved in Homocysteine Metabolism in Malaria Patients in Ouagadougou, Burkina Faso
Table 2
Correlation between genotypes and selected patient characteristics.
| | Genes | Genotypes | Hemoglobin genotypes | | Parasitaemia | | Sex | | | AA | AC | AS | CC | SC | <3000 | 3000–10000 | >10000 | M | F |
| | MTHFR C677T | CC | 20 | 12 | 0 | 2 | 2 | 0.660 | 16 | 6 | 14 | 0.380 | 22 | 14 | 0.457 | | CT | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 4 | 0 | | TT | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| | MTHFR A1298C | AA | 22 | 8 | 2 | 1 | 0 | 0.160 | 11 | 3 | 19 | 0.605 | 26 | 7 | 0.01 | | AC | 2 | 5 | 0 | 0 | 1 | 3 | 2 | 3 | 2 | 6 | | CC | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| | MTR A2756G | AA | 17 | 8 | 1 | 0 | 0 | 0.717 | 4 | 3 | 19 | 0.02 | 19 | 7 | 0.09 | | AG | 6 | 5 | 1 | 1 | 1 | 9 | 2 | 3 | 10 | 4 | | GG | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 2 |
| | MTRR A66G | AA | 14 | 6 | 0 | 0 | 0 | 0.009 | 4 | 2 | 14 | 0.185 | 16 | 4 | 0.182 | | AG | 8 | 8 | 1 | 1 | 1 | 9 | 2 | 8 | 10 | 9 | | GG | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
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