Research Article
Major Polymorphisms of Genes Involved in Homocysteine Metabolism in Malaria Patients in Ouagadougou, Burkina Faso
Table 3
Frequencies of mutations studied in different populations.
| | Country (reference) | Burkina Faso | Pakistan [10] | China [11] | South Korea [12] | Sweden [13] | Brazil [14] | | Genes | Genotypes | % | % | % | % | % | % |
| | MTHFR C677T | CC | 90.0 | 71.3 | 32.8 | 28.5 | 55.9 | 53.8 | | CT | 10.0 | 26.2 | 43.9 | 52.9 | 35.8 | 40.4 | | TT | 0.0 | 2.5 | 23.3 | 18.6 | 8.4 | 5.7 |
| | MTHFR A1298C | AA | 78.6 | 20.8 | 66.8 | 67.8 | — | — | | AC | 19.0 | 48.7 | 29.3 | 30.3 | — | — | | CC | 2.4 | 30.5 | 3.9 | 1.9 | — | — |
| | MTR A2756G | AA | 61.9 | 52.4 | — | — | 64.8 | — | | AG | 33.3 | 38.8 | — | — | 30.9 | — | | GG | 4.8 | 8.8 | — | — | 4.3 | — |
| | MTRR A66G | AA | 50.0 | — | 55.2 | — | 16.7 | — | | AG | 45.0 | — | 38.2 | — | 50.8 | — | | GG | 5.0 | — | 6.6 | — | 32.4 | — |
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