Sustained Effectiveness of a Fixed-Dose Combination of Artesunate and Amodiaquine in 480 Patients with Uncomplicated Plasmodium falciparum Malaria in Côte d’Ivoire

Table 2

Effectiveness: treatment response in the per protocol population.

	Period 1	Period 2
	= 255	= 240
Adequate clinical and parasitological response (ACPR)	244 (95.7%)	231 (96.3%)
Early clinical failure	None	None
Early parasitological failure	None	None
Late clinical failure	3 (1.2%)	2 (0.8%)
Late parasitological failure	None	1 (0.4%)
Not assessable	8 (3.1%)	6 (2.6%)

ACPR and parasitological failure were confirmed by PCR. The proportion of patients with ACPR was not significantly different between the two treatment periods ( = 0.82; Fisher’s exact test).