Research Article

Association between Inflammatory Cytokine Levels and Thrombocytopenia during Plasmodium falciparum and P. vivax Infections in South-Western Coastal Region of India

Table 5

Severe malarial complications in severe thrombocytopenia patients across various infecting species.

Clinical conditionTotal (n=63)P. vivax (n=28)P. falciparum (n=20)Mixed (n=15)p value

Severe anemia11 (17.5)4 (14.3)4 (20)3 (20)0.499
Acute renal failure8 (12.7)4 (14.3)2 (10)2 (13.3)0.063
Jaundice17 (27.0)6 (21.4)5 (25)6 (40)0.063
Metabolic acidosis23 (36.5)12 (42.9)8 (40)3 (20)0.827
Spontaneous bleeding2 (3.2)0 (0)0 (0)2 (13.3)NA
Hypoglycemia16 (25.4)7 (25)6 (30)3 (20)0.134
Hyperparasitemia3 (4.8)0 (0)3 (15)0 (0)NA
Acute respiratory distress syndrome (ARDS)1 (1.6)1 (3.6)0 (0)0 (0)NA
Pulmonary edema12 (19)5 (17.9)4 (20)3 (20)0.498
Cerebral malaria (CM)1 (1.6)1 (3.6)0 (0)0 (0)NA

Data represented as number of patents (percentage) and was compared between three infecting groups by using multinomial proportion test. P < 0.05 was considered to be significant.