Influence of Gold Nanoparticle Shape and Single-Cell Localization on Energy Deposition Efficiency and Irradiation Specificity in Photon Radiotherapy

Figure 1

A single gold nanorod at the center of the water-filled cubic representative volume. In simulations probing the influence of nanoparticle shape, the representative volume contained only a single nanoparticle—either a nanosphere, a nanorod, or a nanoplate—in each simulation run. The size of the representative volume was varied so as to reflect different nanoparticle concentrations.