Influence of Gold Nanoparticle Shape and Single-Cell Localization on Energy Deposition Efficiency and Irradiation Specificity in Photon Radiotherapy

Figure 5

Influence of AuNP shape. Graphs show the dependence of the relative usable fraction of deposited energy with respect to spherical AuNPs Δⁱ (i = rod, plate) on the photon beam energy for the nanosphere diameter of (a) 10 nm, (b) 50 nm, and (c) 100 nm. Nanorods and nanoplates were of the same volume as the nanospheres. For each nanoparticle size, red graphs pertain to gold nanoplates and blue graphs to gold nanorods, while different lines of the same color (solid, dashed, and dotted) refer to three nanoparticle concentrations (20, 7, and 1 (mg Au)/(g H₂O), respectively).

(a)

(b)

(c)