Influence of Gold Nanoparticle Shape and Single-Cell Localization on Energy Deposition Efficiency and Irradiation Specificity in Photon Radiotherapy

Figure 6

Influence of spherical AuNP intracellular localization. Graphs show the dependence of the fraction of deposited energy delivered to the nucleus δⁱ_nucleus on the photon beam energy for nanoparticle concentrations of (a) 1 (mg Au)/(g H₂O), (b) 7 (mg Au)/(g H₂O), and (c) 20 (mg Au)/(g H₂O). At each concentration, graphs of various colors pertain to the five different nanoparticle localizations, while different lines of the same color (solid, dashed, and dotted) refer to three nanoparticle diameters (100, 50, and 10 nm, respectively).

(a)

(b)

(c)