Table of Contents Author Guidelines Submit a Manuscript
Neuroscience Journal
Volume 2013, Article ID 679389, 5 pages
Review Article

rTMS as a Treatment of Alzheimer’s Disease with and without Comorbidity of Depression: A Review

1Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, MB, Canada R3T 5V6
2Graduate Program in Biomedical Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, MB, Canada R3T 5V6
3Riverview Health Center, 1 Morley Avenue, Winnipeg, MB, Canada R3L 2P4

Received 30 November 2012; Accepted 15 January 2013

Academic Editor: Dong-ho Youn

Copyright © 2013 Grant Rutherford et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


With an ever-increasing population of Alzheimer’s disease (AD) patients worldwide, a noninvasive treatment for AD is needed. In this paper, the application of repetitive transcranial magnetic stimulus (rTMS) as a treatment for patients with probable AD is compared to the application of rTMS as a treatment for depression. Comorbidity of depression and dementia is discussed, as well as possible links between the two diseases. The possible confounding antidepressant effects of rTMS on cognitive improvements in AD patients are discussed.