Association of Metabolic Syndrome and Inflammation with Cognitive Decline in Adults Aged 60 Years and Older: Findings from a National Health Survey in the United States
Table 3
Odds ratios (95% CI) of individual MetS traits and the number of MetS for cognitive decline.
Model 1
Model 2
Model 3
OR
(95% CI)
value
OR
(95% CI)
value
OR
(95% CI)
value
Individual MetS traits
Large WC versus small
1.54
(1.23–1.93)
<0.001
1.52
(1.22–1.90)
<0.001
1.52
(1.18–1.95)
0.001
High BP versus low
1.47
(1.14–1.90)
0.003
1.49
(1.15–1.92)
0.003
1.42
(1.05–1.92)
0.024
Decreased HDL-C versus high
1.27
(0.91–1.77)
0.154
1.27
(0.90–1.77)
0.170
1.23
(0.88–1.73)
0.233
Elevated TG versus low
1.24
(0.94–1.64)
0.125
1.25
(0.96–1.64)
0.104
1.23
(0.94–1.61)
0.134
Elevated glucose versus low
1.94
(1.40–2.68)
<0.001
1.87
(1.36–2.57)
<0.001
1.76
(1.23–2.52)
0.002
MetS: Yes versus No
1.41
(1.03–1.92)
0.032
1.40
(1.03–1.90)
0.034
1.68
(1.25–2.24)
0.001
No. of MetS traits
1 versus 0
1.29
(0.78–2.13)
0.328
1.32
(0.79–2.22)
0.294
1.24
(0.60–2.55)
0.568
2 versus 0
1.35
(0.84–2.17)
0.219
1.35
(0.83–2.19)
0.226
1.38
(0.71–2.67)
0.339
3 versus 0
1.72
(1.04–2.85)
0.036
1.72
(1.05–2.81)
0.031
2.02
(1.09–3.75)
0.026
≥4 versus 0
1.88
(1.17–3.02)
0.009
1.90
(1.18–3.06)
0.008
2.25
(1.22–4.16)
0.010
Test for trend
1.16
(1.04–1.29)
0.005
1.16
(1.04–1.28)
0.006
1.24
(1.12–1.38)
<0.001
MetS: metabolic syndrome; WC: waist circumference; BP: blood pressure; HDL-C: high density lipoprotein cholesterol; TG: triglyceride. Model 1: adjusted for age, sex, and race. Model 2: adjusted for covariates in Model 1 plus marital status and smoking status. Model 3: adjusted for covariates in Model 2 plus log-CRP.
