Neuroscience Journal / 2015 / Article / Tab 3

Research Article

Change in Motor and Nonmotor Symptoms Severity in a “Real-Life” Cohort of Subjects with Parkinson’s Disease

Table 3

Comparison of mean scores for MDS-UPDRS, NMSS, and PDQ-8 between initial and follow-up visits according to disease severity.

Initial evaluationFollow-up value

MDS-UPDRS Part I9.57 ± 6.179.11 ± 7.060.570
 Mild 5.17 ± 2.334.96 ± 3.540.765
 Moderate15.11 ± 2.9315.11 ± 2.80≥0.99
 Severe 22.0033.00
MDS-UPDRS Part II11.32 ± 8.1211.32 ± 10.210.99
 Mild 6.13 ± 3.885.58 ± 3.450.479
 Moderate18.50 ± 2.4421.25 ± 5.170.185
 Severe38.0044.00
MDS-UPDRS Part III30.57 ± 16.0123.40 ± 13.70<0.001
 Mild 21.23 ± 7.1215.53 ± 7.23<0.0001
 Moderate46.83 ± 7.9338.83 ± 4.440.159
 Severe
MDS-UPDRS Part IV1.11 ± 2.302.02 ± 2.930.015
 Mild0.48 ± 1.160.93 ± 1.360.017
 Moderate9.50 ± 0.707.00 ± 0.000.126
 Severe
MDS-UPDRS Total51.45 ± 22.5145.84 ± 27.840.068
NMSS38.20 ± 38.9652.48 ± 50.380.043
PDQ-8 21.88 ± 21.2022.88 ± 20.110.575

Mean ± standard deviation. MDS-UPDRS: Movement Disorder Society Unified Parkinson’s Disease Rating Scale. NMSS: Nonmotor Symptom Assessment Scale for Parkinson’s Disease. PDQ-8: Parkinson’s Disease Quality of Life Questionnaire.