Neuroscience Journal / 2015 / Article / Tab 4

Research Article

Change in Motor and Nonmotor Symptoms Severity in a “Real-Life” Cohort of Subjects with Parkinson’s Disease

Table 4

Change in nonmotor symptoms scale score between initial and follow-up visits .

DomainInitial evaluationFollow-up value

Cardiovascular0.46 ± 1.161.02 ± 2.140.142
 Mild0.30 ± 1.190.34 ± 0.740.852
 Moderate0.75 ± 1.161.25 ± 2.760.598
 Severe0.009.00
Sleep/fatigue6.33 ± 8.658.19 ± 8.440.141
 Mild2.50 ± 4.654.23 ± 4.990.095
 Moderate11.75 ± 8.5412.50 ± 7.650.795
 Severe28.0025.00
Mood/cognition9.46 ± 14.4012.40 ± 17.800.172
 Mild2.65 ± 6.805.53 ± 10.350.104
 Moderate14.00 ± 6.9815.62 ± 18.110.787
 Severe18.0062.00
Perceptual problems/hallucinations0.17 ± 0.670.77 ± 2.100.044
 Mild 0.07 ± 0.390.23 ± 0.860.425
 Moderate0.62 ± 1.401.12 ± 1.880.487
 Severe0.0011.00
Attention3.26 ± 6.005.09 ± 7.640.156
 Mild2.26 ± 4.033.11 ± 4.700.438
 Moderate8.12 ± 11.467.25 ± 10.890.782
 Severe2.0036.00
Gastrointestinal tract4.76 ± 6.375.56 ± 7.760.232
 Mild 3.24 ± 4.903.00 ± 6.050.803
 Moderate4.87 ± 5.338.50 ± 8.410.280
 Severe12.0030.00
Urinary function6.17 ± 9.068.65 ± 10.940.240
 Mild2.72 ± 5.194.20 ± 6.530.389
 Moderate10.75 ± 11.7511.75 ± 12.380.884
 Severe12.0036.00
Sexual function2.11 ± 4.693.83 ± 7.810.298
 Mild0.96 ± 2.382.04 ± 5.760.370
 Moderate4.87 ± 8.646.75 ± 9.370.654
 Severe0.0024.00
Miscellaneous4.80 ± 6.566.63 ± 6.380.112
 Mild3.24 ± 5.235.84 ± 6.130.117
 Moderate5.12 ± 4.825.37 ± 6.090.932
 Severe2.0021.00
Total score38.2 ± 38.9652.48 ± 50.380.043
 Mild19.32 ± 23.7728.68 ± 23.060.089
 Moderate60.87 ± 33.2270.12 ± 43.410.606
 Severe74.00254.00

Mean ± standard deviation. Each nonmotor symptom scale domain was subclassified according to the Movement Disorder Society Unified Parkinson’s Disease Rating Scale Part I (Non-Motor Experiences of Daily Living) and cut-off values established by Martínez-Martín et al. [9].