Review Article

Human Cytomegalovirus Latency: Targeting Differences in the Latently Infected Cell with a View to Clearing Latent Infection

Table 1

Cellular miRNAs are regulated during HCMV latency. Following the establishment of HCMV latency in CD34+ progenitor cells, cellular miRNA analysis was carried out using the Invitrogen NCode system [45] which identified a small number of changes.

MicroRNA Fold change during latency
compared to mock
value

hsa-miR-let-7a −2.5 0.005
hsa-miR-let-7b −3.7 0.0001
hsa-miR-206 −2 0.02
hsa-miR-296 3p −2.6 0.007
hsa-miR-297 −2.9 0.001
hsa-miR-32*−2 0.07
hsa-miR-608 −2.4 0.008
hsa-miR-92a −2.5 0.003