Cytochrome c: A Multifunctional Protein Combining Conformational Rigidity with Flexibility

Table 2

Gibbs free energy of hydrogen exchange obtained for the indicated protein segments of horse heart ferricytochrome c reported by Krishna et al. [23].

Foldon	Identity	Δ𝐺HX; [kJ/mol]
Blue bihelix	N- and C-terminal 𝛼-helices	53.5
Green helix and green loop	60’s 𝛼-helix and 19–36 Ω-loop	40.18
Yellow 𝛽-sheet	37–39, 58–61 antiparallel 𝛽-strands	30.71
Red loop	71–85 Ω-loop	26.14
Infrared loop	40–57 Ω-loop	15.8