New Journal of Science / 2016 / Article / Tab 1

Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 1

Reported pharmacokinetic profile of baicalein and baicalin after three oral doses of baicalein and one i.v. dose of baicalein () [4].

Group (mg/kg)ParameterAUC (μg/L h) (μg/L) (h) (h)MRT (h)(%)

50 Baicalein454.3 121.7167.3 73.21.6 0.31.4 1.02.9 0.323.0
Baicalin18366.3 4796.34216.7 1380.73.8 0.54.1 0.85.1 0.4

150 Baicalein1156.1 205.2318.4 51.81.4 0.66.4 3.65.9 0.819.9
Baicalin47654.9 15208.07194.7 4984.54.0 0.84.1 0.57.2 2.5

500 Baicalein2526.9 1537.3612.5 316.02.3 1.213.4 9.56.2 1.513.1
Baicalin104717.4 52674.313687.0 2215.83.5 0.66.5 3.69.0 4.1

i.v. 10 Baicalein7421.5 1079.930409.2 4610.70.0334.8 5.00.4 0.2
Baicalin4389.7 860.46146.6 3363.40.0830.9 0.23.3 0.4