Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 11

Pharmacokinetic parameters after single oral administration of total flavonoids from mulberry leaves (), [13].

ParameterMean SD
RutinIsoquercitrinAstragalinQuercetinKaempferolIsorhamnetin

(ng/mL)51.65 32.28122.66 70.3273.28 40.60132.58 73.396.86 4.6812.50 8.81
(ng/mL) 103.16 62.506.45 2.2111.87 7.74
(h)0.26 0.160.23 0.120.19 0.060.18 0.080.30 0.130.19 0.07
(h)6.75 1.047.75 2.257.25 1.83
(h)1.19 0.620.88 0.610.87 0.526.09 1.678.33 2.8310.03 4.89
(h−1)0.77 0.451.20 0.781.03 0.540.12 0.040.09 0.030.09 0.06
AUC (ng·h/L)85.34 28.8699.51 22.0461.66 31.17755.03 468.2345.90 29.7199.27 58.61
AUC (ng·h/L)85.85 28.81106.38 21.7169.87 33.68772.19 457.9456.20 38.02108.17 58.53