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New Journal of Science
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2016
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Article
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Tab 13
Review Article
A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines
Table 13
Pharmacokinetic parameters after oral administrations of Cortex Juglandis Mandshuricae extract to rats (
) [
15
].
Parameters
(ng/mL)
(h)
(h)
AUC
(ng h/mL)
AUC
(ng h/mL)
LLOQ
(ng/mL)
Gallic acid
3443.76
590.25
11.33
1.63
11.11
1.15
32,197.94
6726.62
33,181.25
7003.57
20
Myricitrin
103.36
8.49
11.33
1.63
10.05
1.63
1009.24
112.15
1105.05
125.02
5.0
Quercitrin
111.29
26.98
8.33
1.97
6.20
1.68
1059.03
160.82
1095.39
154.96
3.0
Taxifolin
110.24
19.17
8.33
2.94
9.58
1.49
914.13
203.48
1090.99
234.24
10
Myricetin
54.10
2.07
8.33
1.97
10.99
1.66
655.64
93.27
767.51
118.48
6.0
Quercetin
33.57
6.50
6.67
1.03
11.09
2.34
328.55
71.38
382.08
77.72
3.0
Naringenin
64.83
28.90
8.67
1.63
11.12
2.85
581.66
224.28
641.38
243.09
2.0
5,8-Dihydroxy-1,4-naphthoquinone
9965.75
1745.38
4.00
0.00
10.38
1.69
63,876.73
1203.66
66,032.97
13,172.50
100