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New Journal of Science
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2016
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Article
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Tab 15
Review Article
A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines
Table 15
Pharmacokinetic parameters after oral administration of EsA in beagle dogs (
) [
17
].
Parameters
Mean
SD
2.5 mg/kg
5 mg/kg
10 mg/kg
(h)
3.7
0.8
5.3
1.0
4.7
1.0
(ng/mL)
281.4
35.2
388.2
51.6
1005
187
(h)
3.5
0.5
3.3
0.4
3.6
0.5
MRT (h)
8.2
0.3
8.1
0.5
7.5
0.5
AUC
(ng h/mL)
3036
218
4496
340
6828
757
AUC
(ng h/mL)
3085
226
4557
340
6941
792