Review Article
A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines
Table 15
Pharmacokinetic parameters after oral administration of EsA in beagle dogs (
) [
17].
| | Parameters | Mean SD | | 2.5 mg/kg | 5 mg/kg | 10 mg/kg |
| | (h) | 3.7 0.8 | 5.3 1.0 | 4.7 1.0 | | (ng/mL) | 281.4 35.2 | 388.2 51.6 | 1005 187 | | (h) | 3.5 0.5 | 3.3 0.4 | 3.6 0.5 | | MRT (h) | 8.2 0.3 | 8.1 0.5 | 7.5 0.5 | | AUC (ng h/mL) | 3036 218 | 4496 340 | 6828 757 | | AUC (ng h/mL) | 3085 226 | 4557 340 | 6941 792 |
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