New Journal of Science / 2016 / Article / Tab 16

Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 16

Pharmacokinetic parameters after oral administration of total extract from Dioscorea zingiberensis C.H. Wright () [18].

ParametersProtodioscinHuangjiangsu AZingiberensis DioscinGracillin

(ng/mL)29.18 1.8314.87 1.4614.87 1.4638.24 0.63130.86 1.90
(h)11.98 2.4511.43 3.2410.32 2.1710.29 1.1912.79 2.49
(h)15.86 2.1311.04 2.0317.04 2.0312.79 1.6637.29 1.82
(h−1)0.044 1.010.063 1.980.041 3.320.054 2.840.019 3.72
MRT (h)18.15 1.8321.06 2.3048.61 1.7325.87 0.7457.99 1.15
CL (L/h)0.21 0.020.23 0.020.06 0.0040.11 0.010.01 0.003
AUC (h ng/mL)6473.11 821.05291.31 21.14291.31 21.1419990.91 727.16106902.70 2118.13
AUC (h ng/mL)9098.37 1656.586747.44 1504.586747.44 1504.5828379.48 2066.52469583.7 24463.47