New Journal of Science / 2016 / Article / Tab 17

Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 17

Pharmacokinetic parameters of PD and PD3 after intravenous (25 mg/kg) or oral administration of PD (500 mg/kg) to rats () [19].

ParameterPDPD3

Intravenous
AUC (μg·h/mL)11.42 3.431.96 0.50
(h)1.99 0.413.55 0.87
MRT (h)1.58 0.412.85 0.77
(L/kg)3.59 1.2835.32 18.69
CL (L/h/kg)2.32 0.9011.84 27.77

Oral
AUC (μg·h/mL)0.66 0.360.53 0.31
(h)6.23 1.846.20 1.05
(μg/mL)0.22 0.220.20 0.24
(h)0.75 (0.17–3)0.48 (0.11–1.61)

Data are mean SD (standard deviation). Median (ranges).