New Journal of Science / 2016 / Article / Tab 20

Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 20

Pharmacokinetic parameters after oral administration of Aralia-saponin V, Aralia-saponin VI, and the extract of A. elata leaves [21].

ParametersAralia-saponin VAralia-saponin
VI
 Extract of Aralia  elata leaves
Aralia-saponin
V
Aralia-saponin
VI

(ng/mL)161.8 ± 20.19188.55 ± 35.35174.5 ± 5.21192.59 ± 18.7
(h)1.08 ± 0.190.88 ± 0.131.04 ± 0.090.88 ± 0.13
0.10 ± 0.030.09 ± 0.010.16 ± 0.070.09 ± 0.02
(h)7.33 ± 2.597.45 ± 0.614.92 ± 1.897.92 ± 1.67
AUC (ng/mL/h)796.0 ± 135.6932.45 ± 95.92915.7 ± 79.71024.69 ± 112.5
AUC (ng/mL/h)1156.9 ± 286.61306.74 ± 160.241210.3 ± 211.41516.73 ± 197.68
LLOQ (ng/mL)5.706.15