A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 20

Pharmacokinetic parameters after oral administration of Aralia-saponin V, Aralia-saponin VI, and the extract of A. elata leaves [21].

Parameters	Aralia-saponin V	Aralia-saponin; VI	Extract of Aralia  elata leaves
			Aralia-saponin; V	Aralia-saponin; VI
(ng/mL)	161.8 ± 20.19	188.55 ± 35.35	174.5 ± 5.21	192.59 ± 18.7
(h)	1.08 ± 0.19	0.88 ± 0.13	1.04 ± 0.09	0.88 ± 0.13
	0.10 ± 0.03	0.09 ± 0.01	0.16 ± 0.07	0.09 ± 0.02
(h)	7.33 ± 2.59	7.45 ± 0.61	4.92 ± 1.89	7.92 ± 1.67
AUC (ng/mL/h)	796.0 ± 135.6	932.45 ± 95.92	915.7 ± 79.7	1024.69 ± 112.5
AUC (ng/mL/h)	1156.9 ± 286.6	1306.74 ± 160.24	1210.3 ± 211.4	1516.73 ± 197.68
LLOQ (ng/mL)	5.70	6.15	—	—